Anti-HIF-3 alpha

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R31264	100 µg		-	-	3 - 10 business days*		755.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. Hypoxia-inducible factor 3 alpha, also... more

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Product information "Anti-HIF-3 alpha"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. This gene involved in adaptive response to hypoxia. HIF3a suppresses hypoxia-inducible expression of HIF1a and HIF2a. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element(HRE) of target gene promoters. The complex HIF3a-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea. Protein function: Acts as a transcriptional regulator in adaptive response to low oxygen tension. Acts as a regulator of hypoxia-inducible gene expression (PubMed:11573933, PubMed:16126907, PubMed:19694616, PubMed:20416395, PubMed:21069422). Functions as an inhibitor of angiogenesis in hypoxic cells of the cornea. Plays a role in the development of the cardiorespiratory system. May also be involved in apoptosis. [The UniProt Consortium]

Keywords:	Anti-IPAS, Anti-bHLHe17, Anti-BHLHE17, Anti-HIF3-alpha, Anti-HIF-3-alpha, Anti-HIF3-alpha-1, Anti-Member of PAS protein 7, Anti-Inhibitory PAS domain protein, Anti-PAS domain-containing protein 7, Anti-Hypoxia-inducible factor 3-alpha, HIF-3 alpha Antibod
Supplier:	NSJ Bioreagents
Supplier-Nr:	R31264

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat
Immunogen:	An amino acid sequence from the C-terminus of human HIF3A (DDDFQLNASEQLPRAYHR) was used as the immunogen for this HIF-3 alpha antibody.
Format:	Purified