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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA055599.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
ATA-HPA055599.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcriptional repressor which binds preferentially to the canonical E box... more
Product information "Anti-HEY1"
Protein function: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 95%
Keywords: | Anti-HEY1, Anti-hHRT1, Anti-HRT-1, Anti-CHF-2, Anti-HESR-1, Anti-BHLHB31, Anti-bHLHb31, Anti-HES-related repressor protein 1, Anti-Hairy-related transcription factor 1, Anti-Cardiovascular helix-loop-helix factor 2 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA055599 |
Properties
Application: | IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: HLNNYASQRE AASGAHAGLG HIPWGTVFGH HPHIAHPLLL PQNGHGNAGT TASPTEPHHQ G (ATA-APrEST78558) |
Database Information
KEGG ID : | K09091 | Matching products |
UniProt ID : | Q9Y5J3 | Matching products |
Gene ID | GeneID 23462 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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