Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
H1827-55.200 | 200 µg | - | - |
3 - 19 business days* |
985.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Acetylation and deacetylation of core histone lysine residues, by histone acetyltransferases... more
Product information "Anti-HDAC3 (Histone Deacetylase-3)"
Acetylation and deacetylation of core histone lysine residues, by histone acetyltransferases (HAT) and histone deacetylases (HDAC) respectively, have been shown to be necessary for some crucial nuclear events such as gene transcription, DNA replication and repair. HDACs are found in multi-protein complexes with transcriptional co-repressors such as mSin3, RbAp46/48, SMRT, and NCoR. HDAC3, which is over 50% identical to both HDAC1 and HDAC2, is ubiquitously expressed and exhibits histone deacetylase activity, represses transcription and associates with the transcription factor YY1. The identification of a family of functionally redundant HDACs suggests each may have a unique function, supported by the sequence divergence of the carboxy-termini. , , Applications: Immunoblot Analysis: 1-4ug/ml detected HDAC3 from a HeLa RIPA cell lysate (1 hour exposure). 4ug/ml detected HDAC from mouse WEHI and rat L6 RIPA cell lysates (30 minute exposure). Immunoblot Analysis HeLa cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-HDAC3 (1ug/ml). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | H1827-55 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | chicken, human, mouse, rat |
Format: | Affinity Purified |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed