Anti-GSTA2, NT (GSTA2, GST2, Glutathione S-transferase A2, GST HA subunit 2, GST class-alpha member

Anti-GSTA2, NT (GSTA2, GST2, Glutathione S-transferase A2, GST HA subunit 2, GST class-alpha member
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036335-HRP.200 200 µl - -

3 - 19 business days*

731.00€
 
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct... more
Product information "Anti-GSTA2, NT (GSTA2, GST2, Glutathione S-transferase A2, GST HA subunit 2, GST class-alpha member"
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:50-100, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-GTH2, Anti-GST2, Anti-GSTA2, Anti-GSTA2-2, Anti-GST-gamma, EC=2.5.1.18, Anti-GST HA subunit 2, Anti-GST class-alpha member 2, Anti-Glutathione S-transferase A2
Supplier: United States Biological
Supplier-Nr: 036335-HRP

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: GSTA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human GSTA2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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