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This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. Protein function: Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness (PubMed:25990725). [The UniProt Consortium]
Keywords:
Anti-GRWD, Anti-GRWD1, Anti-Glutamate-rich WD repeat-containing protein 1, GRWD1 Polyclonal Antibody
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