Anti-GRO gamma (Growth-regulated Protein gamma, GROg, Chemokine (C-X-C Motif) Ligand 3, C-X-C Motif

GRO-gamma, otherwise known as CXCL3, is a 7.9kD CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils. Like GRO-alpha (CXCL1) and GRO-beta (CXCL2), GRO-gamma contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, though studies have shown a difference in the potency and receptor binding affinity of these three proteins. , Applications:, Suitable for use in ELISA, Functional Assays, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 0.5-2ug/ml, Western Blot: 0.1-0.2ug/ml, Functional Assays: 1-2ug/ml, Immunohistochemistry: paraffin sections, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C for short-term only.Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.