Anti-GRO beta (Growth-regulated Protein beta, Gro-beta, GROb, Chemokine (C-X-C Motif) Ligand 2, CXCL

GRO-beta, otherwise known as CXCL2, is a 7.9kD CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils. Like GRO-alpha (CXCL1) and GRO-gamma (CXCL3), GRO-beta contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, though studies have shown that GRO-beta has a lower potency and receptor binding affinity. , Applications:, Suitable for use in ELISA, Functional Assays, and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5ug/ml, Western Blot: 0.1-0.2ug/ml, Functional Assays: 0.5-1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C for short-term only.Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.