Anti-GRCR1

This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains, these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010], Protein function: May play a role in actin filament architecture in developing stereocilia of sensory cells. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cell projection, stereocilium . Cell projection, microvillus . Cell projection, kinocilium . In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. .