Anti-GRB7

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA057084.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA057084.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Adapter protein that interacts with the cytoplasmic domain of numerous receptor... more

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Product information "Anti-GRB7"

Protein function: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 57% and to rat: 59%

Keywords:	Anti-B47, Anti-GRB7, Anti-GRB7 adapter protein, Anti-Growth factor receptor-bound protein 7, Anti-Epidermal growth factor receptor GRB-7
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA057084

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: QGHTTGSVKP LSRSDAMELD LSPPHLSSSP EDLCPAPGTP PGTPRPPDTP LPEEVKRSQP LLIPTTGRKL (ATA-APrEST88847)