Anti-GPx8 (human) (IN103)

Anti-GPx8 (human) (IN103)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-25B-0028-C100 100 µg -

3 - 9 business days*

374.00€
 
Recognizes human GPx8. GPxs are glutathione peroxidases involved in balancing the H2O2... more
Product information "Anti-GPx8 (human) (IN103)"
Recognizes human GPx8. GPxs are glutathione peroxidases involved in balancing the H2O2 homeostasis in signaling cascades. GPxs have been known to catalyze the reduction of H2O2 or organic hydroperoxides to water or the corresponding alcohols, respectively, typically using glutathione (GSH) as reductant. GPx8 (probable glutathione peroxidase 8) is a 209-aa, 24kDa protein with an N-terminal cytosolic tip, a predicted transmembrane segment and a catalytic domain located in the endoplasmic reticulum (ER) lumen. GPx8 is a CysGPxs with low glutathione peroxidase activity. A recent study identified GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. GPx8 cleavage by NS3-4A occurs at Cys11, removing the cytosolic tip of GPx8 and was observed in different experimental systems as well as in liver biopsies from patients with chronic hepatitis C.
Keywords: Anti-GPX8, Anti-GPx-8, Anti-GSHPx-8, EC=1.11.1.9, Anti-Probable glutathione peroxidase 8
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-25B-0028

Properties

Application: WB, ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant GPx8 (human) (aa 38-209) fused to a GST-tag.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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