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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in... more
Product information "Anti-GOT1"
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Protein function: Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. [The UniProt Consortium]
Keywords: | Anti-GOT1, Anti-cCAT, Anti-cAspAT, EC=2.6.1.1, EC=2.6.1.3, Anti-Transaminase A, Anti-Cysteine transaminase, cytoplasmic, Anti-Glutamate oxaloacetate transaminase 1, Anti-Cysteine aminotransferase, cytoplasmic, Anti-Aspartate aminotransferase, cytoplasmic, |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-61133 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human GOT1 |
Database Information
KEGG ID : | K14454 | Matching products |
UniProt ID : | P17174 | Matching products |
Gene ID | GeneID 2805 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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