Anti-GNA13

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA010087.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA010087.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or... more

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Product information "Anti-GNA13"

Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 95%

Keywords:	Anti-GNA13, Anti-G alpha-13, Anti-G-protein subunit alpha-13, Anti-Guanine nucleotide-binding protein subunit alpha-13
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA010087

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: HGQDFDQRAR EEFRPTIYSN VIKGMRVLVD AREKLHIPWG DNSNQQHGDK MMSFDTRAPM AAQGMVETRV FLQYLPAIRA LWADSGIQNA YDRRREFQLG ES (ATA-APrEST72476)