Anti-GMNN

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA049977.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA049977.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into... more

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Product information "Anti-GMNN"

Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) (PubMed:9635433, PubMed:14993212, PubMed:20129055, PubMed:24064211). It is degraded during the mitotic phase of the cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Its destruction at the metaphase- anaphase transition permits replication in the succeeding cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing (PubMed:20129055). Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control (PubMed:22615398). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 90% and to rat: 88%

Keywords:	Anti-GMNN, Anti-Geminin
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA049977

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RRKALYEALK ENEKLHKEIE QKDNEIARLK KENKELAEVA EHVQYMAELI ERLNGEPLDN (ATA-APrEST85402)