Anti-GLIS2, ID (GLIS2, NKL, Zinc finger protein GLIS2, GLI-similar 2, Neuronal Krueppel-like protein

Anti-GLIS2, ID (GLIS2, NKL, Zinc finger protein GLIS2, GLI-similar 2, Neuronal Krueppel-like protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036081-HRP.200 200 µl - -

3 - 19 business days*

721.00€
 
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear... more
Product information "Anti-GLIS2, ID (GLIS2, NKL, Zinc finger protein GLIS2, GLI-similar 2, Neuronal Krueppel-like protein"
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-NKL, Anti-GLIS2, Anti-GLI-similar 2, Anti-Zinc finger protein GLIS2, Anti-Neuronal Krueppel-like protein
Supplier: United States Biological
Supplier-Nr: 036081-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: GLIS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-202 amino acids from the Central region of human GLIS2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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