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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2427.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2427.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the GIT protein family, which interact with G protein-coupled... more
Product information "Anti-GIT2"
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G Protein function: GTPase-activating protein for ADP ribosylation factor family members, including ARF1. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: nucleoplasm,focal adhesion,
Keywords: | Anti-GIT2, Anti-CAT2, Anti-CAT-2, Anti-KIAA0148, Anti-ARF GAP GIT2, Anti-GRK-interacting protein 2, Anti-ARF GTPase-activating protein GIT2, Anti-G protein-coupled receptor kinase-interactor 2, Anti-Cool-interacting tyrosine-phosphorylated protein 2, GIT2 |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2427 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human GIT2. AA range:361-410 |
MW: | 84 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K12487 | Matching products |
UniProt ID : | Q14161 | Matching products |
Gene ID | GeneID 9815 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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