Anti-GEMIN7

Anti-GEMIN7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-19115.20 20 µl -

7 - 16 business days*

71.00€
E-AB-19115.60 60 µl -

7 - 16 business days*

143.00€
E-AB-19115.120 120 µl -

7 - 16 business days*

238.00€
E-AB-19115.200 200 µl -

7 - 16 business days*

396.00€
 
The protein encoded by this gene is a component of the core SMN complex, which is required for... more
Product information "Anti-GEMIN7"
The protein encoded by this gene is a component of the core SMN complex, which is required for pre-mRNA splicing in the nucleus. The encoded protein is found in the nucleoplasm, in nuclear "gems" (Gemini of Cajal bodies), and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. [The UniProt Consortium]
Keywords: Anti-SIP3, Anti-GEMIN7, Anti-Gemin-7, Anti-Gem-associated protein 7, GEMIN7 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-19115

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Fusion protein of human GEMIN7

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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