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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-325A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-325A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear... more
Product information "Anti-Gemin5"
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. GEMIN5 acts as the snRNA-binding protein of the SMN complex. [The UniProt Consortium]
Keywords: | Anti-GEMIN5, Anti-Gemin5, Anti-Gem-associated protein 5 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-325A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by A301-325A-T maps to a region between residue 1360 and 1410 of human gem (nuclear organelle) associated protein 5 using the numbering given in entry NP_056280.1 (GeneID 25929). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K13133 | Matching products |
UniProt ID : | Q8TEQ6 | Matching products |
Gene ID | GeneID 25929 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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