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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R30537 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glial cell-derived neurotrophic factor, is... more
Product information "Anti-GDNF"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glial cell-derived neurotrophic factor, is a protein that, in humans, is encoded by the GDNF gene. It is a small protein that potently promotes the survival of many types of neurons and a founding member of the GDNF family of ligands(GFL). The gene is mapped to human chromosome 5p13.1-p12 by fluorescence in situ hybridization(FISH). This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosisof motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET(rearranged during transfection) protooncogene. Protein function: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. [The UniProt Consortium]
Keywords: | Anti-ATF, Anti-GDNF, Anti-hGDNF, Anti-Astrocyte-derived trophic factor, Anti-Glial cell line-derived neurotrophic factor, GDNF Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R30537 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat |
Immunogen: | An amino acid sequence from the middle region of human GDNF (FRYCSGSCDAAETTYDK) |
Format: | Purified |
Database Information
KEGG ID : | K05452 | Matching products |
UniProt ID : | P39905 | Matching products |
Gene ID | GeneID 2668 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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