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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES4047.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES4047.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members... more
Product information "Anti-GDI-2"
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008], Protein function: GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking (PubMed:25860027). Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A (PubMed:25860027). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Cytoplasm . Membrane , Peripheral membrane protein .
Keywords: | Anti-GDI2, Anti-GDI-2, Anti-RABGDIB, Anti-Rab GDI beta, Anti-Rab GDP dissociation inhibitor beta, Anti-Guanosine diphosphate dissociation inhibitor 2, GDI-2 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES4047 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthesized peptide derived from the C-terminal region of human GDI-2. |
MW: | 50 kD |
Format: | Purified |
Database Information
KEGG ID : | K17255 | Matching products |
UniProt ID : | P50395 | Matching products |
Gene ID | GeneID 2665 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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