Anti-GATA1 (Ab-142)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1397-100	100 µg		-		3 - 11 business days*		682.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein... more

Close menu

Product information "Anti-GATA1 (Ab-142)"

GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Protein function: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781). [The UniProt Consortium]

Keywords:	Anti-GF-1, Anti-GATA1, Anti-Eryf1, Anti-ERYF1, Anti-GATA-1, Anti-GATA-binding factor 1, Anti-NF-E1 DNA-binding protein, Anti-Erythroid transcription factor, Polyclonal Antibody to GATA1 (Ab-142)
Supplier:	Abeomics
Supplier-Nr:	35-1397

Properties

Application:	WB, IHC, IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around aa.140~144 (R-L-S-P-D) derived from Human GATA1.
Format:	Purified