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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-CAB3968.50 | 50 µl | - | - |
9 - 20 business days* |
352.00€
|
||
| G-CAB3968.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: ATP- and magnesium-dependent helicase that plays an essential role in innate... more
Product information "Anti-G3BP1"
Protein function: ATP- and magnesium-dependent helicase that plays an essential role in innate immunity (PubMed:30510222). Participates in the DNA- triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA (PubMed:30804210). In addition, plays an essential role in stress granule formation (PubMed:12642610, PubMed:20180778, PubMed:23279204). Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends (PubMed:9889278). Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency (PubMed:9889278). Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA (PubMed:9889278). Phosphorylation-dependent sequence-specific endoribonuclease in vitro (PubMed:11604510). Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR (PubMed:11604510). [The UniProt Consortium]
| Keywords: | Anti-G3BP, Anti-G3BP1, Anti-G3BP-1, Anti-hDH VIII, Anti-ATP-dependent DNA helicase VIII, Anti-GAP SH3 domain-binding protein 1, Anti-Ras GTPase-activating protein-binding protein 1, G3BP1 Rabbit mAb |
| Supplier: | Assay Genie |
| Supplier-Nr: | CAB3968 |
Properties
| Application: | WB, IF, IP |
| Antibody Type: | Monoclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
Database Information
| KEGG ID : | K17265 | Matching products |
| UniProt ID : | Q13283 | Matching products |
| Gene ID | GeneID 10146 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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