Anti-FZR1, NT (FZR1, CDH1, FYR, FZR, KIAA1242, Fizzy-related protein homolog, CDC20-like protein 1,

Anti-FZR1, NT (FZR1, CDH1, FYR, FZR, KIAA1242, Fizzy-related protein homolog, CDC20-like protein 1,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
035824-HRP.200 200 µl - -

3 - 19 business days*

721.00€
 
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which... more
Product information "Anti-FZR1, NT (FZR1, CDH1, FYR, FZR, KIAA1242, Fizzy-related protein homolog, CDC20-like protein 1,"
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-Fzr, Anti-CDH1, Anti-FZR1, Anti-hCDH1, Anti-Cdh1/Hct1 homolog, Anti-CDC20-like protein 1, Anti-Fizzy-related protein homolog
Supplier: United States Biological
Supplier-Nr: 035824-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: FZR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human FZR1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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