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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V8958SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. The Fos related gene, Fra-2, was initially... more
Product information "Anti-FRA2 / FOSL2, clone PCRP-FOSL2-1B1"
1 mg/ml in 1X PBS, BSA free, sodium azide free. The Fos related gene, Fra-2, was initially molecularly cloned from chicken genomic DNA and shown to represent a new member of the immediate early gene family. The human counterpart of the chicken Fra-2 gene has since been described. Sequence alignment shows that the amino acid sequences conserved among Fra-2, c-Fos, Fra-1 and Fos B are contained in five regions. Region 2, the longest and most highly conserved region, contains the leucine zipper structure and the basic region, suggesting that like Fos, Fra-1 and Fos B, Fra-2 also forms heterodimers with c-Jun that recognize a specific DNA sequence such as the binding site for transcription factor AP-1. Such a model is further supported by the finding that the Fra-2 gene product forms a complex with c-Jun in growth-stimulated cells Protein function: Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts. [The UniProt Consortium]
Keywords: | Anti-FRA2, Anti-FRA-2, Anti-FOSL2, Anti-Fos-related antigen 2, FRA2 Antibody / FOSL2 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V8958SAF |
Properties
Application: | FC, IF |
Antibody Type: | Monoclonal |
Clone: | PCRP-FOSL2-1B1 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant full-length human FOSL2 protein |
Format: | Purified |
Database Information
KEGG ID : | K09030 | Matching products |
UniProt ID : | P15408 | Matching products |
Gene ID | GeneID 2355 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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