Anti-FOXL2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA069613.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA069613.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Transcriptional regulator. Critical factor essential for ovary differentiation... more

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Product information "Anti-FOXL2"

Protein function: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans- differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen. Is a regulator of CYP19 expression. Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element. Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 79%

Keywords:	Anti-FOXL2, Anti-Forkhead box protein L2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA069613

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MMASYPEPED AAGALLAPET GRTVKEPEGP PPSPGKGG (ATA-APrEST88584)