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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES16361.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES16361.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the major facilitator superfamily. The encoded transmembrane... more
Product information "Anti-FLVC2"
This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Aug 2010], Protein function: Putative heme b importer/sensor involved in heme homeostasis in response to the metabolic state of the cell and to diet. May act as a sensor of cytosolic and/or mitochondrial heme levels to regulate mitochondrial respiration processes, ATP synthesis and thermogenesis. At low heme levels, interacts with components of electron transfer chain (ETC) complexes and ATP2A2, leading to ubiquitin-mediated degradation of ATP2A2 and inhibition of thermogenesis. Upon heme binding, dissociates from ETC complexes to allow switching from mitochondrial ATP synthesis to thermogenesis. Alternatively, in coordination with ATP2A2 may mediate calcium transport and signaling in response to heme. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cell membrane, Multi-pass membrane protein.
Keywords: | Anti-CCT, Anti-FLVCR2, Anti-C14orf58, Anti-Heme transporter FLVCR2, Anti-Calcium-chelate transporter, Anti-Feline leukemia virus subgroup C receptor-related protein 2, FLVC2 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES16361 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthesized peptide derived from human FLVC2 AA range: 352-402 |
Format: | Purified |
Database Information
KEGG ID : | K08220 | Matching products |
UniProt ID : | Q9UPI3 | Matching products |
Gene ID | GeneID 55640 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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