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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES11404.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES11404.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the major facilitator superfamily of transporter proteins. The... more
Product information "Anti-FLVC1"
This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome. [provided by RefSeq, Jan 2011], Protein function: [Isoform 1]: Heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment. Heme export depends on the presence of HPX and is required to maintain intracellular free heme balance, protecting cells from heme toxicity. Heme export provides protection from heme or ferrous iron toxicities in liver, brain, sensory neurons and during erythropoiesis, a process in which heme synthesis intensifies. Possibly export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. The molecular mechanism of heme transport, whether electrogenic, electroneutral or coupled to other ions, remains to be elucidated. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: [Isoform 1]: Cell membrane , Multi-pass membrane protein ., [Isoform 2]: Mitochondrion membrane , Multi-pass membrane protein .
Keywords: | Anti-hFLVCR, Anti-Heme transporter FLVCR1, Anti-Feline leukemia virus subgroup C receptor, Anti-Feline leukemia virus subgroup C receptor-related protein 1, FLVC1 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES11404 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | Synthesized peptide derived from human protein . at AA range: 481-530 |
MW: | 61 kD |
Format: | Purified |
Database Information
KEGG ID : | K08220 | Matching products |
UniProt ID : | Q9Y5Y0 | Matching products |
Gene ID | GeneID 28982 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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