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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-CAB13880.50 | 50 µl | - | - |
9 - 20 business days* |
352.00€
|
||
G-CAB13880.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
WB 1:500 - 1:2000. Protein function: Component of the cleavage factor Im (CFIm) complex that... more
Product information "Anti-FLJ12529"
WB 1:500 - 1:2000. Protein function: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs (PubMed:8626397, PubMed:17024186, PubMed:29276085). CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'- end, so called cleavage and polyadenylation signals (pA signals) (PubMed:8626397, PubMed:17024186). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation (PubMed:23187700, PubMed:29276085). The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'- untranslated region (UTR) for a huge number of pre-mRNAs (PubMed:20695905, PubMed:29276085). CPSF7 activates directly the mRNA 3'-processing machinery (PubMed:29276085). Binds to pA signals in RNA substrates (PubMed:8626397, PubMed:17024186). [The UniProt Consortium]
Keywords: | Anti-CFIm59, Anti-CPSF 59 kDa subunit, Anti-Cleavage factor Im complex 59 kDa subunit, Anti-Pre-mRNA cleavage factor Im 59 kDa subunit, Anti-Cleavage and polyadenylation specificity factor subunit 7, FLJ12529 Polyclonal Antibody (CAB13880) |
Supplier: | Assay Genie |
Supplier-Nr: | CAB13880 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Database Information
KEGG ID : | K14398 | Matching products |
UniProt ID : | Q8N684 | Matching products |
Gene ID | GeneID 79869 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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