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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is a cis-trans peptidyl-prolyl isomerase that may function in... more
Product information "Anti-FKBP6"
The protein encoded by this gene is a cis-trans peptidyl-prolyl isomerase that may function in immunoregulation and basic cellular processes involving protein folding and trafficking. This gene is located in a chromosomal region that is deleted in Williams-Beuren syndrome. Defects in this gene may cause male infertility. There are multiple pseudogenes for this gene located nearby on chromosome 7. Alternative splicing results in multiple transcript variants. Protein function: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes. [The UniProt Consortium]
Keywords: | Anti-FKBP6, Anti-FKBP-6, Anti-FKBP36, Anti-FKBP-36, Anti-36 kDa FKBP, Anti-Immunophilin FKBP36, Anti-Inactive PPIase FKBP6, Anti-FK506-binding protein 6, Anti-36 kDa FK506-binding protein, Anti-Inactive peptidyl-prolyl cis-trans isomerase FKBP6, FKBP6 Pol |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-61468 |
Properties
Application: | WB, IHC, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human FKBP6 |
Database Information
KEGG ID : | K09572 | Matching products |
UniProt ID : | O75344 | Matching products |
Gene ID | GeneID 8468 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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