Anti-Fibrillarin, clone 38F3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG52280.50	50 µl		-	-	6 - 14 business days*		592.00€

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Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to... more

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Product information "Anti-Fibrillarin, clone 38F3"

Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (PubMed:1825809). Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Involved in the biogenesis of the 18S rRNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239). [The UniProt Consortium]

Keywords:	Anti-NOP1, Anti-LOT3, Anti-D2870, Anti-YDL014W, Anti-Nucleolar protein 1, Anti-U3 snoRNA-associated protein NOP1, Anti-Histone-glutamine methyltransferase, Anti-rRNA 2'-O-methyltransferase fibrillarin, Anti-U3 small nucleolar RNA-associated protein NOP1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG52280

Properties

Application:	ICC, IF, IHC (frozen), WB
Antibody Type:	Monoclonal
Clone:	38F3
Conjugate:	No
Host:	Mouse
Species reactivity:	human, c. elegans, D. melanogaster , plant, s. pombe
Immunogen:	Yeast nuclear preparations
Format:	Purified