Anti-FHL2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1860-50	50 µl		-		3 - 11 business days*		574.00€

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May function as a molecular transmitter linking various signaling pathways to transcriptional... more

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Product information "Anti-FHL2"

May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Genini M., Schwalbe P., Scholl F.A., Remppis A., Mattei M.-G., Schaefer B.W.DNA Cell Biol. 16:433-442(1997) Protein function: May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008). [The UniProt Consortium]

Keywords:	Anti-FHL2, Anti-DRAL, Anti-FHL-2, Anti-SLIM-3, Anti-LIM domain protein DRAL, Anti-Skeletal muscle LIM-protein 3, Anti-Four and a half LIM domains protein 2, Polyclonal Antibody to FHL2
Supplier:	Abeomics
Supplier-Nr:	35-1860-50

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Peptide sequence around aa.16~28 (I-L-R-E-E) derived from Human FHL2.
Format:	Purified