Anti-FCHO2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA037685.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA037685.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Functions in an early step of clathrin-mediated endocytosis. Has both a... more

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Product information "Anti-FCHO2"

Protein function: Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2- dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 99%

Keywords:	Anti-FCHO2, Anti-F-BAR domain only protein 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA037685

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KAAVKSKKAT DTYKLYVEKY ALAKADFEQK MTETAQKFQD IEETHLIHIK EIIGSLSNAI KEIHLQIG (ATA-APrEST80057)