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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-PACO09260.50 | 50 µl | - |
9 - 20 business days* |
491.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
FBXO9 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human,... more
Product information "Anti-FBXO9"
FBXO9 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, WB, IHC applications. FBXO9 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1. [The UniProt Consortium]
Keywords: | Anti-FBX9, Anti-FBXO9, Anti-F-box only protein 9, Anti-Cross-immune reaction antigen 1, Anti-Renal carcinoma antigen NY-REN-57 |
Supplier: | Assay Genie |
Supplier-Nr: | PACO09260 |
Properties
Application: | ELISA, WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Human FBXO9 |
Database Information
KEGG ID : | K10295 | Matching products |
UniProt ID : | Q9UK97 | Matching products |
Gene ID | GeneID 26268 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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