Anti-FAM65B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
G-CAB9234.50	50 µl		-	-	9 - 20 business days*		352.00€
G-CAB9234.100	100 µl		-		9 - 20 business days*		448.00€

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WB 1:500 - 1:2000. Protein function: Acts as an inhibitor of the small GTPase RHOA and plays... more

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Product information "Anti-FAM65B"

WB 1:500 - 1:2000. Protein function: Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (PubMed:17150207, PubMed:24687993, PubMed:23241886, PubMed:24958875, PubMed:25588844, PubMed:27556504). Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration (PubMed:23241886). Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion. Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear. Plays a role for maintaining the structural organization of the basal domain of stereocilia. Involved in mechanosensory hair cell function. Required for normal hearing (PubMed:24958875). [The UniProt Consortium]

Keywords:	Anti-RIPOR2, Anti-Rho family-interacting cell polarization regulator 2, FAM65B Polyclonal Antibody (CAB9234)
Supplier:	Assay Genie
Supplier-Nr:	CAB9234

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human FAM65B (NP_056948.2).