Anti-FAM175A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA037654.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Involved in DNA damage response and double-strand break (DSB) repair. Component... more

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Product information "Anti-FAM175A"

Protein function: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 51% and to rat: 50%

Keywords:	Anti-Protein FAM175A, Anti-BRCA1-A complex subunit Abraxas 1, Anti-Coiled-coil domain-containing protein 98
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA037654

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: CNYNHHLDVV DNLTLMVEHT DIPEASPAST PQIIKHKTLD LDDRWQFKRS RLLDTQDKRS KADTGSSNQD KASKMSSPET DEEIEKMKGF GEYSRSPT (ATA-APrEST87240)