Anti-EZH1, N-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG63241.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex,... more

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Product information "Anti-EZH1, N-terminal"

Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. [The UniProt Consortium]

Keywords:	Anti-EZH1, Anti-ENX-2, Anti-KIAA0388, EC=2.1.1.43, Anti-Enhancer of zeste homolog 1, Anti-Histone-lysine N-methyltransferase EZH1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG63241

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, bovine)
Immunogen:	EIPNPPTSKCITY
Format:	Ammonium Sulfate Precipitated