Anti-Erythropoietin Receptor (EPOr)

Human Erythropoietin Receptor (EPOr) is located on stem and mature cells of the hematopoietic system. When activated by its native ligand, Erythropoietin, EPOr mediates proliferation and maturation of the erythroid precursor cells leading to expansion of red cell populations. Human recombinant EPO is currently used for treatment of patients undergoing erythrocyte depletion due to dialysis for kidney failure. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile (40-50%) glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.