Anti-ERI1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA056074.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA056074.100	100 µl		-		7 - 10 business days*		446.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them,... more

Close menu

Product information "Anti-ERI1"

Protein function: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'- ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 97%

Keywords:	Anti-ERI1, Anti-HEXO, EC=3.1.-.-, Anti-Eri-1 homolog, Anti-Protein 3'hExo, Anti-3'-5' exonuclease ERI1, Anti-3'-5' exoribonuclease 1, Anti-Histone mRNA 3'-exonuclease 1, Anti-Histone mRNA 3'-end-specific exoribonuclease
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA056074

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ELRAKLSEFK LETRGVKDVL KKRLKNYYKK QKLMLKESNF ADSYYDYICI IDFEATCEE (ATA-APrEST87745)