Anti-ERCC1, clone CL1284

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ATA-AMAb90872.25	25 µl		-		7 - 10 business days*		15 %	240.00€ 204.00€
ATA-AMAb90872.100	100 µl		-		7 - 10 business days*		15 %	358.00€ 304.30€

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Protein function: [Isoform 1]: Non-catalytic component of a structure-specific DNA repair... more

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Product information "Anti-ERCC1, clone CL1284"

Protein function: [Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. [The UniProt Consortium] Validated by genetic and standard strategies. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 93%. Epitope specificity: KARRLFDVLH.

Keywords:	Anti-ERCC1, Anti-DNA excision repair protein ERCC-1
Supplier:	Atlas Antibodies
Supplier-Nr:	AMAb90872

Properties

Application:	IHC, WB
Antibody Type:	Monoclonal
Clone:	CL1284
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LADCTLILAW SPEEAGRYLE TYKAYEQKPA DLLMEKLEQD FVSRVTECLT TVKSVNKTDS QTLLTTFGSL EQLIAASRED LALCPGLGPQ KARRLFDVLH EPFLKVP (ATA-APrEST93708)