Anti-EPHB2 (Ephrin Type-B Receptor 2, Tyrosine-protein Kinase Receptor EPH-3, DRT, Receptor Protein-

Anti-EPHB2 (Ephrin Type-B Receptor 2, Tyrosine-protein Kinase Receptor EPH-3, DRT, Receptor Protein-
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E3371-02N.200 200 µl - -

3 - 19 business days*

728.00€
 
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes,... more
Product information "Anti-EPHB2 (Ephrin Type-B Receptor 2, Tyrosine-protein Kinase Receptor EPH-3, DRT, Receptor Protein-"
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain. Applications: Suitable for use in ELISA, Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, Immunohistochemistry (FFPE): 1:200, Flow Cytometry: 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-DRT, Anti-EK5, Anti-hEK5, Anti-EPHB2, EC=2.7.10.1, Anti-EPH-like kinase 5, Anti-EPH tyrosine kinase 3, Anti-Ephrin type-B receptor 2, Anti-ELK-related tyrosine kinase, Anti-Tyrosine-protein kinase TYRO5, Anti-Renal carcinoma antigen NY-REN-47
Supplier: United States Biological
Supplier-Nr: E3371-02N

Properties

Application: ELISA, FC, IHC, WB
Antibody Type: Monoclonal
Clone: 10i37
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Purified His-tagged EPHB2 protein (fragment).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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