Anti-EphA5, clone 46CT61.6.4

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG57558.100 100 µl - -

6 - 14 business days*

474.00€
 
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A... more
Product information "Anti-EphA5, clone 46CT61.6.4"
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino- hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose- stimulated insulin secretion. [The UniProt Consortium]
Keywords: Anti-BSK, Anti-EK7, Anti-hEK7, Anti-EHK-1, Anti-EPHA5, EC=2.7.10.1, Anti-EPH-like kinase 7, Anti-EPH homology kinase 1, Anti-Brain-specific kinase, Anti-Ephrin type-A receptor 5
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG57558

Properties

Application: IHC (paraffin), WB
Antibody Type: Monoclonal
Clone: 46CT61.6.4
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified His-tagged EphA5 protein fragment
MW: 115 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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