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Promotion:
Save 30% on all primary antibodies by Arigo Biolaboratories!
*1
*1 Offer expires 16/12/2024
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ARG57558.100 | 100 µl | - | - |
6 - 14 business days* |
30 %
|
584.00€
408.80€ |
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A... more
Product information "Anti-EphA5, clone 46CT61.6.4"
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino- hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose- stimulated insulin secretion. [The UniProt Consortium]
Keywords: | Anti-BSK, Anti-EK7, Anti-hEK7, Anti-EHK-1, Anti-EPHA5, EC=2.7.10.1, Anti-EPH-like kinase 7, Anti-EPH homology kinase 1, Anti-Brain-specific kinase, Anti-Ephrin type-A receptor 5 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG57558 |
Properties
Application: | IHC (paraffin), WB |
Antibody Type: | Monoclonal |
Clone: | 46CT61.6.4 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Purified His-tagged EphA5 protein fragment |
MW: | 115 kD |
Format: | Purified |
Database Information
KEGG ID : | K05106 | Matching products |
UniProt ID : | P54756 | Matching products |
Gene ID | GeneID 2044 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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