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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-CAB19229.50 | 50 µl | - |
9 - 20 business days* |
352.00€
|
|||
G-CAB19229.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B... more
Product information "Anti-Eph receptor B3 (EPHB3)"
Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt. [The UniProt Consortium]
Keywords: | Anti-EK2, Anti-ETK2, Anti-hEK2, Anti-EPHB3, EC=2.7.10.1, Anti-EPH-like kinase 2, Anti-Embryonic kinase 2, Anti-Ephrin type-B receptor 3, Anti-EPH-like tyrosine kinase 2, Anti-Tyrosine-protein kinase TYRO6, Eph receptor B3 (EPHB3) Rabbit mAb |
Supplier: | Assay Genie |
Supplier-Nr: | CAB19229 |
Properties
Antibody Type: | Monoclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human Eph receptor B3 (EPHB3) (EPHB3). |
Database Information
KEGG ID : | K05112 | Matching products |
UniProt ID : | P54753 | Matching products |
Gene ID | GeneID 2049 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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