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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E2287-03A.100 | 100 µg | - | - |
3 - 19 business days* |
834.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Endoglin is a homodimeric integral membrane glycoprotein comprised of 95kD subunit. Endoglin is a... more
Product information "Anti-Endoglin (CD105, END, Endoglin, FLJ41744, HHT1, ORW, ORW1)"
Endoglin is a homodimeric integral membrane glycoprotein comprised of 95kD subunit. Endoglin is a component of the TGF-B receptor system that functions as an ancillary receptor influencing binding of the Transforming Growth Factor beta (TGF-B) family ligands to signaling receptors. Endoglin binds TGF-B1 and TGF-B3 with high affinity but does not bind TGF-B2. Endoglin is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta and is weakly expressed by stromalfibroblasts. It is also expressed by U937 cells and activated macrophages. Endoglin expression is up regulated on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation. Applications: Suitable for use in Flow Cytometry, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 detected Endoglin on 10ug of Jurkat lysates, Immunohistochemistry: For use on acetone or paraformaldehyde fixed tissue., Optimal dilutions to be determined by the researcher. Positive Control: Jurkat cell lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-ENG |
Supplier: | United States Biological |
Supplier-Nr: | E2287-03A |
Properties
Application: | ELISA, FC, ICC, IHC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | 9H229 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Human resting umbilical vein endothelial cells. Cellular Localization: Membrane, Single-pass type I membrane protein. |
Format: | Purified |
Database Information
KEGG ID : | K06526 | Matching products |
UniProt ID : | P17813 | Matching products |
Gene ID | GeneID 2022 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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