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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E2058-50B.100 | 100 µg | - | - |
3 - 19 business days* |
901.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD39L4, also called ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5), ERUDPase and PCPH,... more
Product information "Anti-Ectonucleoside Triphosphate Diphosphohydrolase 5 (ENTPD5, CD39 Antigen-like 4, CD39L4, ER-UDPas"
CD39L4, also called ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5), ERUDPase and PCPH, is a secreted, 45-51kD class II member of the GDA1/CD39 NTPase family of molecules. It is expressed by multiple cell types, including neurons, cardiomyocytes, and hepatocytes. CD39L4 is a divalent cation dependent enzyme that preferentially hydrolyzes GDP and UDP. In the ER, this enzyme may remove UDP which interferes with proper protein folding and maturation. Extracellularly, CD39L4 may reduce available UDP ligand for P2Y receptors. Mature human CD39L4 is a 408aa glycoprotein (aa21-428). It contains four APR (apyrase conserved regions) (aa54-206) that participate in NTPase activity. CD39L4 has been reported to exist as both monomer and homodimer. Three potential splice variants are reported. One shows a seven aa substitution for aa401-428, a second contains a five aa substitution for aa401-428, and a third possesses a 22aa substitution for aa215-428. Over aa21-428, human CD39L4 shares 89% aa sequence identity with mouse CD39L4. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-ENTPD5, Anti-CD39L4, Anti-ER-UDPase, Anti-NTPDase 5, EC=3.6.1.6, EC=3.6.1.42, Anti-GDPase ENTPD5, Anti-UDPase ENTPD5, Anti-CD39 antigen-like 4, Anti-Nucleoside diphosphatase, Anti-Uridine-diphosphatase ENTPD5, Anti-Guanosine-diphosphatase ENTPD5 |
Supplier: | United States Biological |
Supplier-Nr: | E2058-50B |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 12K84 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to aa21-428 from human ENTPD5 expressed in CHO cell line. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K01511 | Matching products |
UniProt ID : | O75356 | Matching products |
Gene ID | GeneID 957 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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