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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES16891.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES16891.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the... more
Product information "Anti-DSC1"
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015], Protein function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cell membrane, Single-pass type I membrane protein. Cell junction, desmosome.
Keywords: | Anti-DSC1, Anti-CDHF1, Anti-DG2/DG3, Anti-Desmocollin-1, Anti-Cadherin family member 1, Anti-Desmosomal glycoprotein 2/3, DSC1 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES16891 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human DSC1 AA range: 749-799 |
Format: | Purified |
Database Information
KEGG ID : | K07600 | Matching products |
UniProt ID : | Q08554 | Matching products |
Gene ID | GeneID 1823 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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