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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ7115 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Drebrin is a protein that in humans is... more
Product information "Anti-Drebrin 1, clone 4F6E7"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. Protein function: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMed:20215400). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines. Involved in memory-related synaptic plasticity in the hippocampus. [The UniProt Consortium]
Keywords: | Anti-DBN1, Anti-Drebrin, Anti-D0S117E, Anti-Developmentally-regulated brain protein, Drebrin 1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ7115 |
Properties
Application: | WB, IHC (paraffin), FC |
Antibody Type: | Monoclonal |
Clone: | 4F6E7 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat, monkey |
Immunogen: | Recombinant human protein (amino acids H9-D649) |
Format: | Purified |
Database Information
KEGG ID : | K25391 | Matching products |
UniProt ID : | Q16643 | Matching products |
Gene ID | GeneID 1627 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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