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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ7372 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. This gene is a member of the dedicator of... more
Product information "Anti-DOCK4 / Dedicator of cytokinesis protein 4"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. Protein function: Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (PubMed:12628187, PubMed:16464467). Involved in regulation of adherens junction between cells (PubMed:12628187). Plays a role in cell migration (PubMed:20679435). [The UniProt Consortium]
Keywords: | Anti-DOCK4, Anti-KIAA0716, Anti-Dedicator of cytokinesis protein 4, DOCK4 Antibody / Dedicator of cytokinesis protein 4 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ7372 |
Properties
Application: | WB, IHC (paraffin), FC, Direct ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat |
Immunogen: | recombinant human protein (amino acids K191-I1837) |
Format: | Purified |
Database Information
KEGG ID : | K17697 | Matching products |
UniProt ID : | Q8N1I0 | Matching products |
Gene ID | GeneID 9732 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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