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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES16916.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES16916.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a... more
Product information "Anti-DOCK4"
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008], Protein function: Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (PubMed:12628187, PubMed:16464467). Involved in regulation of adherens junction between cells (PubMed:12628187). Plays a role in cell migration (PubMed:20679435). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cell membrane . Cell projection . Cytoplasm, cytosol . Colocalizes with EPHA2, RHOG and CTTN/cortactin at the tip of protrusions in migrating cells. .
Keywords: | Anti-DOCK4, Anti-KIAA0716, Anti-Dedicator of cytokinesis protein 4, DOCK4 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES16916 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human DOCK4 AA range: 533-583 |
Format: | Purified |
Database Information
KEGG ID : | K17697 | Matching products |
UniProt ID : | Q8N1I0 | Matching products |
Gene ID | GeneID 9732 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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