Anti-DOCK180

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-288A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A301-288A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic... more

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Product information "Anti-DOCK180"

Protein function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152). [The UniProt Consortium]

Keywords:	Anti-DOCK1, Anti-DOCK180, Anti-180 kDa protein downstream of CRK, Anti-Dedicator of cytokinesis protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-288A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, west indian ocean coelacanth, white-tufted-ear marmoset, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-288A-T maps to a region between residue 1815 and 1865 of human dedicator of cytokinesis, 180 kDa using the numbering given in entry NP_001371.1 (GeneID 1793).
Format:	Antigen Affinity Purified