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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BOT-BNUM1898-50 | 50 µl | - |
Request delivery time estimate |
565.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The specificity of this monoclonal antibody to its intended target was validated by... more
Product information "Anti-DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), BSA-free, 1 mg/mL"
The specificity of this monoclonal antibody to its intended target was validated by HuProt(TM)Array, containing more than 19,000, full-length human proteins. DNMT3A is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.Primary antibodies are available purified, or with a selection of fluorescent CF(R) Dyes and other labels. CF(R) Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF(R)405S and CF(R)405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. Concentration: 1 mg/mL Storage buffer: PBS, no BSA, no azide
Keywords: | DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), BSA-free, 1 mg/mL, |
Supplier: | Biotium |
Supplier-Nr: | BNUM1898 |
Properties
Application: | IHC (paraffin) (verif.) |
Conjugate: | No |
Format: | Purified, BSA-free |
Database Information
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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