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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG55200.50 | 50 µl | - | - |
6 - 14 business days* |
436.00€
|
||
ARG55200.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Functions in mitochondrial and peroxisomal division. Mediates membrane fission... more
Product information "Anti-DNM1L / DRP1"
Protein function: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Plays an important role in mitochondrial fission during mitosis (PubMed:26992161). Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. [The UniProt Consortium]
Keywords: | Anti-DLP1, Anti-DVLP, Anti-DNM1L, Anti-Dymple, Anti-HdynIV, EC=3.6.5.5, Anti-Dynamin-like protein, Anti-Dynamin-1-like protein, Anti-Dynamin-like protein 4, Anti-Dynamin-like protein IV, Anti-Dnm1p/Vps1p-like protein, Anti-Dynamin-related protein 1 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG55200 |
Properties
Application: | ICC, IF, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Recombinant protein of Human DNM1L (Swiss: O00429) |
MW: | 79 kD |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K17065 | Matching products |
UniProt ID : | O00429 | Matching products |
Gene ID | GeneID 10059 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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